Benjamin T. Bikman, Ph.D.
Department of Cell Biology and Physiology
Education
- Postdoctoral Fellow, Cardiovascular and Metabolic Diseases, Duke-NUS Graduate Medical School, Singapore (2011)
- Ph.D., Bioenergetics, East Carolina University, Greenville, North Carolina (2008)
- M.Sc., Exercise Physiology, Brigham Young University, Provo, Utah (2005)
- B.Sc., Exercise Science, Brigham Young University, Provo, Utah (2003)
Professional Experience
Brigham Young University, Provo, UT
Professor, Department of Cell Biology and Physiology (09/22–Present)
Associate Professor, Department of Physiology and Developmental Biology (07/17–08/22)
Assistant Professor, Department of Physiology and Developmental Biology (07/11–06/17)
East Carolina University, Greenville, NC
Graduate Instructor, Department of Exercise Science (08/2007–12/2007)
Awards, Honors and Recognition
Faculty
- Distinguished Faculty Award (2025)
- APS Research Career Enhancement Award (2013)
- APS/NSF Mentor Award (2013)
- Oroboros Travel Award, O2K Workshop (2012)
Postdoctoral
- Travel Scholarship, Keystone Symposium — Lipid Biology and Lipotoxicity (2011)
Graduate School
- Valedictorian, Department of Exercise Sciences, BYU (2005)
- Dean’s List, Department of Exercise Sciences, BYU (2003–2005)
Undergraduate
- Sloan Speech Showcase: Public Speaking Award, BYU (2002)
- Undergraduate Academic Scholarship, BYU (2000–2002)
Funding
Current
- Sponsored Research Agreement — The endocrine effects of allulose. Total costs: $93,000. Role: PI.
- NIH R15 — RAGE targeting attenuates smoke-induced inflammation. Total costs: $300,000. Role: Co-Investigator.
In Review
—
Completed
- Sponsored Research Agreement — Understanding the hyperglycemia of low-carbohydrate diets. Total costs: $130,000. Role: PI.
- BYU Gerontology Grant — The role of ketones in improving brain function. Total costs: $10,000. Role: PI.
- Sponsored Research Agreement — The effects of chlorophyll on protecting against pollution-induced inflammation. Total costs: $58,272. Role: Co-PI.
- BYU Interdisciplinary Research Award — Diabetes, Arthritis, and Alzheimer’s Disease. Total costs: $120,000. Role: Collaborator.
- Bobbitt Heart Research Award — Etiology of heart development. Total costs: $5,000. Role: Co-I.
- Sponsored Research Agreement — Unicity: anti-oxidant cocktail to mitigate ROS. Total costs: $60,000. Role: Co-PI.
- BYU Mentoring Environment Grant — ketones on adipocyte mitochondrial uncoupling. Total costs: $20,000. Role: PI.
- Bobbitt Heart Research Award — ceramides in heart failure. Total costs: $13,000. Role: PI.
- BYU Gerontology Research Grant Award — A Role for Ceramides in Sarcopenia. Total costs: $10,000. Role: PI.
- BYU Mentoring Environment Grant — TLR4/MyD88 signaling in cigarette smoke-induced heart ceramide accrual. Total costs: $20,000. Role: PI.
- BYU Life Sciences Translational Research Grant — TGFβ inhibition via SGI-1252. Total costs: $15,000. Role: PI.
BYU Diabetes Research Lab
- 2018: $120,000 — including a $110,000 donation to established endowments
- 2017: $114,000 — including a $100,000 donation to established endowments
- 2016: $156,000 — including donations to establish two endowments
- College of Physical and Mathematical Sciences (2014): $15,000
- 2015: $37,000 (various sources)
Student Funding
- 2022 BYU HBLL Award — The bioenergetics of the brain. Total costs: $1,000. Awardee: Erin Saito
- 2019 BYU CURA — β-hydroxybutyrate on brain mitochondrial function. Total costs: $1,500. Awardee: Lance Good
- 2017 BYU ORCA — orally ingested β-hydroxybutyrate in skeletal muscle. Total costs: $1,500. Awardee: Brian Parker
- 2016 BYU Graduate Research Fellowship — insulin in Alzheimer disease etiology. Total costs: $10,000. Awardee: Sheryl Carr
- 2016 BYU ORCA — TGF-Beta inhibition via SGI-1252. Total costs: $1,500. Awardee: Blake Dallon
- 2013 APS/NSF Undergraduate Research Fellowship — ROS and Mitochondrial Fission. Total costs: $4,000. Awardee: Braden Tucker
- 2013 BYU Graduate Research Fellowship — ceramides & smoke-induced metabolic disruption. Total costs: $15,000. Awardee: Mikayla Thatcher
- 2013 BYU ORCA — Ceramides and Oxidative Stress. Total costs: $1,000. Awardee: Braden Tucker
- 2012 BYU ORCA — Ceramides and AMPK. Total costs: $1,000. Awardee: Kate Erickson
- 2012 Graduate Research Fellowship — Ceramides and Mitochondrial Function. Total costs: $15,000. Awardee: Melissa Smith
Service
Journal Reviewer
- Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association
- Experimental and Clinical Endocrinology & Diabetes
- Nature Metabolism
- International Journal of Molecular Science
- Journal of Biological Chemistry
- Journal of Lipid Research
- Diabetology and Metabolic Syndrome
- PloS One
- American Journal of Physiology: Regulatory, Integrative, and Comparative Physiology
- International Journal of Sports Medicine
- Journal of Gerontology: Medical Science
- Life Sciences Journal
- BMC Public Health
- Scientific Reports – Nature
- Journal of Applied Physiology, Nutrition, and Metabolism
Journal Leadership
- 2022–present: General Editor, Journal of Metabolic Health
- 2020–2022: General Topic Editor, International Journal of Molecular Science
- 2018–2022: Lead guest editor, International Journal of Molecular Science — “Effects of Ketones on Metabolic Function”
- 2017–2020: Editorial board member, Journal of Insulin Resistance
- 2016–2017: Guest editor, International Journal of Molecular Science — “Inhaled Pollutants Modulate Respiratory and Systemic Diseases”
- 2015–2016: Lead guest editor, Journal of Diabetes Research — “The Role of Inhaled Pollution in the Etiology of Insulin Resistance”
- 2006–2008: Assistant Editor, The International Journal of Sports Medicine
Grant Reviewer
- 2019: Auckland Medical Research Foundation
- 2016: CSR NIH Early Career Reviewer Program
- 2016–2015: Maratona de Saude — Cardiovascular Complications of Diabetes and Metabolism (Portugal)
- UK Diabetes Fund (England)
Society Leadership and Service
- 2024: American Diabetes Society — Co-director (ongoing)
- 2016: Experimental Biology — Co-Chair (ended 2021)
- 2016: International Association of Medical Science Educators — Nutrition Objectives Group Member (ended 2022)
- 2015: American Physiology Society — Translational Physiology Interest Group Planning Committee Member (ended 2023)
- 2011: Keystone Symposium — conference assistant (Ireland)
- 2010: Asia-Pacific Diabetes Obesity Study Group — Chair (Singapore)
- Postdoctoral representative — Duke-NUS recruitment committee
University Appointments and Administrative Responsibilities
- 2023: Chair — Department Rank & Status Committee
- 2020: Chair — Department Research Committee (ended 2022)
- 2019: Department search committee member; Teaching and Learning Task Force peer reviewer
- 2018: Department search committee member
- 2017: College Faculty Consultant (LSAC); Department Search Committee Member
- 2015: College ORCA Reviewer
- 2014: Department Research Committee Member; College MEG Review Committee Chair; Department Safety Officer; College Safety Committee
- 2013: College MEG Review Committee; Department Safety Officer
- 2012: Department search committee member; Department Safety Officer
- 2011: Department Safety Officer
- 2010: Session Chair — Asia-Pacific Diabetes Obesity Study Group (Singapore)
General University Service
- 2023: Faculty Advisor — BYU Calisthenics Club (ongoing); Gerontology Faculty Affiliate (ongoing)
- 2017: Faculty advisor — BYU Strong Barbell Club (ended 2018)
- 2016: Director — BYU Diabetes Research Lab (ongoing); Education Week Presenter
- 2015: Education Week Presenter; Organizer/Director — BYU Sugar Rush 5K (ongoing)
- 2014: UCUR Moderator
Community and Government Service
- 2025: Advisor — panel to update federal Dietary Guidelines for Americans
- 2023: Advisor — Provo City School District (School Nutrition) & Utah County Public Health
Graduate Student Thesis/Dissertation Committees
- 2025: Eliza Roeth (Thesis Committee Chair – CELL)
- 2023: Jillana AhLoe; Adonica Tuitama (committee member)
- 2022: Cali Warren (Chair – CELL; graduated 2024)
- 2020: Nathan Zuniga; Landon Deru; Christopher Mendoza (committee member)
- 2019: Lynda Guildford (committee member)
- 2018: Chase Walton (Chair – PDBIO; graduated 2020); Erin Saito (Chair – PDBIO); Jacob Herring (member)
- 2016: Sheryl Carr (Chair – PDBIO; graduated 2016); Kevin Steed; BreAnna Hutchinson; Brandon Rose (member)
- 2015: Aimee Hodson (Chair – PDBIO; graduated 2016); Bradley Naylor; Carri Draney (member)
- 2014: Nidhi Choksi; Trevor Tippetts (Chair – PDBIO; graduated 2015); Kai Li Ong (member)
- 2013: Seung Ook Yang; Courtney Banks; Michael Nelson; Amy Crandall; Chen Ting; Duane Winden (member)
- 2012: Melissa Smith (Chair – PDBIO; graduated 2014); Mikayla Thatcher (Chair – PDBIO; graduated 2015); Shalene Hardman; Kevin Tuttle (member)
- 2011: Shenali De Silva (member)
Consulting
- Ketone Labs
- RxSugar Advisory Board
- Unicity Advisory Board
Professional and Scientific Societies
Membership
- Mitochondrial Physiology Society
- American Diabetes Association
- American Physiology Society
- American Society for Investigative Pathology
Teaching
Brigham Young University
- CELL305 — Physiology (2024–present)
- CELL570 — Responsible conduct and research ethics; selected lectures (2022–present)
- CELL565 — Endocrinology (2022–present)
- CELL601 — Cell and Molecular Physiology (2013–2021)
- CELL365 — Pathophysiology (2012–present)
- CELL2/495R — Research Methods (2012–present)
East Carolina University
- EXSS8330 — Advanced Topics in Metabolism, selected lectures (2008)
- EXSS3805 — Physiology of Exercise (2007)
Presentations
Invited University and Professional Presentations
1. 2025 The American Heritage Foundation – Washington DCPresentation: “The metabolic origins of chronic disease”
2. 2025 National University of Singapore – Yong Loo Lin School of MedicinePresentation: “The Life of the Fat Cell”
3. 2025 Barrington White HousePresentation: “Why we get sick”
4. 2025 Brigham Young University – Gerontology ProgramPresentation: “The metabolism of cognitive decline”
5. 2025 Auburn University – School of Nursing Distinguished Lecture SeriesPresentation: “The metabolic origins of chronic disease”
6. 2025 Arizona State UniversityPresentation: “The metabolism of cognitive decline”
7. 2024 National Grazing Land’s Coalition – Regenerating Public HealthPresentation: “Why we get sick”
8. 2024 Rocky Mountain UniversityPresentation: “Insulin Resistance and Metabolic Health”
9. 2024 Society for Functional Diagnostic NutritionPresentation: “Is Allulose Nature’s Ozempic?”
10. 2024 Harvard Business SchoolPresentation: “GLP-1: Drugs and Natural Agonists”
11. 2024 Intermountain Health – Cardiovascular Unit Grand RoundsPresentation: “The metabolic origins of heart disease”
12. 2024 Public Health Collaboration UKPresentation: “The metabolism of longevity”
13. 2024 Massachusetts Institute of Technology – Alumni AssociationPresentation: “Why we get sick”
14. 2024 Cardiometabolic Health CongressPresentation: “Definition and Pathophysiology and Type 2 Diabetes”
15. 2024 Symposium for Metabolic Health PractitionersPresentation: “Shrinking fat cells: Insulin vs. Energy”
16. 2024 Institute for Human and Machine CognitionPresentation: “Why we get sick”
17. 2024 Medical University of South CarolinaPresentation: “Insulin vs. Ketones: The battle for brown fat”
18. 2023 Swiss RE (Switzerland)Presentation: “Insulin resistance and disease: the clinical view”
19. 2023 Kenya Cardiac Society of Africa (Kenya)Presentation: “The metabolic origins of heart disease”
20. 2023 Utah Chapter of the Association of Nurse Practitioners and Physician’s AssistantsPresentation: “Flipping the switch”
21. 2023 Association for the Advancement of Restorative MedicinePresentation: “Insulin resistance and its role in chronic disease”
22. 2023 Peterson AcademyPresentation: “Why we get sick: The metabolic origins of chronic disease”
23. 2023 Utah Valley University – Physician Assistant ProgramPresentation: “Why we get sick: Insulin resistance and how to diagnose it”
24. 2023 MARA Technological University Medical School (Malaysia)Presentation: “Drug therapies for insulin resistance”
25. 2023 Symposium of Metabolic Health PractitionersPresentation: “The myths and misunderstandings of physiological insulin resistance”
26. 2022 Noorda School of MedicinePresentation: “Insulin resistance and disease: the clinical view”
27. 2022 Society of Metabolic Health Practitioners – Grand RoundsPresentation: “Insulin resistance – Cause and Consequence”
28. 2022 Advanced Practice Providers – Grand RoundsPresentation: “Why we get sick and what to do about it”
29. 2022 Dallas-Fort Worth Physicians’ Group – Grand RoundsPresentation: “Insulin resistance and disease: the clinical view”
30. 2022 Annual Meeting of the Illinois Obesity SocietyPresentation: “Hyperinsulinemia and Obesity”
31. 2022 American Association of Nurse Practitioners and Physician’s AssistantsPresentation: “The causes and consequences of insulin resistance”
32. 2022 Utah HOSA Future Health Professionals – Annual MeetingPresentation: “Why we get sick and what to do about it”
33. 2022 Metabolix Israel – Israel Endocrine ConferencePresentation: “Why we get sick: the role of insulin resistance in chronic disease”
34. 2021 Revere Health Grande RoundsPresentation: “The metabolic origins of heart disease”
35. 2021 Penn State University – Department of BiochemistryPresentation: “Understanding insulin resistance”
36. 2021 Stanford University – Department of BioengineeringPresentation: “The cause and consequence of insulin resistance”
37. 2021 Environmental Health SummitPresentation: “The Second Pandemic: Insulin resistance and the plagues of prosperity”
38. 2021 American Specialty Health SymposiaPresentation: “Why we get sick and what to do about it”
39. 2021 Metabolix – Israel Endocrine ConferencePresentation: “Flipping the switch: From insulin resistance to diabetes”
40. 2021 United States Navy Medical Professionals – Physicians’ Grand RoundsPresentation: “Flipping the switch: from insulin resistance to diabetes”
41. 2020 International Medical University, Kuala Lumpur, MalaysiaPresentation: “The role of insulin resistance in chronic disease”
42. 2019 The Friedman Center for Breast and Lymphatic SurgeryPresentation: “Why we get sick”
43. 2019 East Carolina University – Diabetes and Metabolism Research CenterPresentation: “Ceramides and Mitochondria”
44. 2019 BYU Marriott School of ManagementPresentation: “Misguided Medicine: Why we get sick and fat”
45. 2018 Thailand Medical Professional Seminar – BangkokPresentation: “Ketones: A metabolic advantage”
46. 2018 University of UtahPresentation: “Arylhydratase receptors as mediators of pollution-induced heart ceramide accrual”
47. 2018 Brigham Young University – Forum AddressPresentation: “The plagues of prosperity”
48. 2018 Duke–National University of SingaporePresentation: “Insulin vs. Ketones: The battle for brown fat”
49. 2018 Autism Hope AwarenessInterview: “The role of sugar in chronic diseases”
50. 2018 Cotton Tree Family Practice – Grand RoundsPresentation: “Why we get sick and fat”
51. 2018 Chinese University of Hong KongPresentation: “The Air We Breathe: The effects of Diesel Exhaust on Macrophage Mitochondrial Bioenergetics”
52. 2017 Oman Medical Professional SeminarPresentation: “Insulin resistance: the plague of prosperity”
53. 2016 Timpanogos Regional Hospital – Grand RoundsPresentation: “Why we get sick: the role of insulin resistance in chronic disease”
54. 2016 Thailand Medical ProfessionalsPresentation: “Why we get sick: Insulin resistance and chronic disease”
55. 2015 University of Louisville – Diabetes and Obesity CenterPresentation: “Ceramides mediate metabolic disruption following inhaled pollution”
56. 2015 Roseman University of Health SciencesPresentation: “The pathology of insulin resistance”
57. 2014 Brigham Young University – Cancer Research ProgramPresentation: “Ceramides, Mitochondria, and Cancer”
58. 2013 Southwest Chapter of ACSMPresentation: “The role of ceramides as a mediator of metabolic disruption”
59. 2013 University of Utah – Vascular Research LaboratoryPresentation: “The Role of Sphingolipids in Metabolic Disruption”
60. 2013 Salt Lake City – ARUP LaboratoriesPresentation: “Insulin Resistance: The Great Mediator”
61. 2011 Brigham Young University – Department of Nutrition and Food SciencePresentation: “Ceramide as a Regulator of Obesity and Metabolism”
62. 2010 Brigham Young University – Department of Physiology and Developmental Biology Lecture SeriesPresentation: “Between a Rock and a Hard Place: Ceramide as a Mediator of Inflammation-induced Insulin Resistance”
63. 2007 East Carolina University – Metabolic Institute for Obesity and Diabetes ResearchPresentation: “Does AMPK Inhibit NF-κB in Skeletal Muscle?”
Invited Scientific Meeting Presentations
1. 2022 American Association of Biological AnthropologyPresentation: “The energy demands of the brain and how we got it wrong”
2. 2020 Obesity and Lymphatics Disorders SummitPresentation: “Insulin and Lipedema: Fat Where It Doesn’t Belong”
3. 2020 American College of Sports Medicine Annual MeetingPresentation: “Insulin vs. Ketones: The battle for brown fat”
4. 2020 Metabolic Health SummitPresentation: “A new paradigm for type 2 diabetes”
5. 2018 American Society of Integrative PathologyPresentation: “Insulin vs. Ketones: Contrasting effects on brown adipose tissue”
6. 2016 American College of Sports Medicine Annual MeetingPresentation: “Ceramides Force Fission”
7. 2016 Experimental BiologyPresentation: “Mitochondrial fission is necessary for ceramide-induced metabolic disruption”
8. 2015 American Physiological Society – Physiological BioenergeticsPresentation: “Sphingolipid accrual is necessary for LPS-induced mitochondrial disruption”
Scientific Meetings
1. 2023 Society for Developmental Biology (poster)Presentation: “The effects of RAGE up-regulation during pulmonary morphogenesis”
2. 2022 European/American Physiological Society (poster)Presentation: “Beyond the lung: The effect of cigarette smoke on inflammation-induced insulin resistance”
3. 2022 Experimental Biology (poster)Presentation: “Hormonal response to macronutrients in the context of a low-carbohydrate diet”
4. 2022 Experimental Biology (poster)Presentation: “Ketogenic diet increases movement and speed in mice”
5. 2022 Experimental Biology (poster)Presentation: “Ketogenic diet improves neuron mitochondrial bioenergetics in mice”
6. 2021 Experimental Biology (oral)Presentation: “Alzheimer’s disease alters oligodendrocytic glycolytic and ketolytic gene expression”
7. 2021 Experimental Biology (poster)Presentation: “Smoke exposure compromises sperm mitochondrial bioenergetics”
8. 2020 Experimental Biology (poster)Presentation: “Metabolic RNA-seq profiles from sporadic Alzheimer’s disease patients: Analysis of glycolytic and ketolytic pathways”
9. 2020 Experimental Biology (poster)Presentation: “Selective androgen receptor modulation with MK-2866 favorably alters muscle mitochondrial bioenergetics”
10. 2020 Experimental Biology (poster)Presentation: “4-HNE unfavorably alters muscle mitochondrial bioenergetics and cell viability”
11. 2019 Experimental Biology (poster)Presentation: “Effect of beta-hydroxybutyrate on myoblast proliferation and differentiation”
12. 2018 Keystone Symposia – Diabetes Mellitus (oral)Presentation: “Beta-hydroxybutyrate favorably alters beta-cell survival and mitochondrial bioenergetics”
13. 2018 Experimental Biology (oral)Presentation: “The contrasting effects of ketones on mitochondrial function in muscle and adipose”
14. 2018 Experimental Biology (oral)Presentation: “The role of ketones on adipocyte mitochondrial uncoupling”
15. 2017 Experimental Biology (poster)Presentation: “Nasal administration of diesel exhaust particles does not evoke inflammation, endothelial dysfunction, or initiate autophagy in murine femoral arteries”
16. 2017 Experimental Biology (poster)Presentation: “Beta-hydroxybutyrate favorably alters muscle cell survival and mitochondrial bioenergetics”
17. 2017 Experimental Biology (poster)Presentation: “Beta-hydroxybutyrate favorably alters beta-cell survival and mitochondrial bioenergetics”
18. 2017 Experimental Biology (poster)Presentation: “SGI-1252, a TGF-beta inhibitor, protects against diet-induced obesity and insulin resistance in mice”
19. 2017 Experimental Biology (oral)Presentation: “Insulin alters brain lipid profile and mitochondrial function”
20. 2017 Experimental Biology (oral)Presentation: “Diesel exhaust particle exposure compromises macrophage mitochondrial physiology”
21. 2016 Experimental Biology (poster)Presentation: “Treatment with diet or insulin induces a different placental ceramide expression during gestational diabetes mellitus”
22. 2016 Experimental Biology (poster)Presentation: “Acylation of SOD1 provides tool to determine if mitochondrial aggregation of SOD1 is main driver of ALS”
23. 2016 Experimental Biology (oral)Presentation: “Insulin treatment increases myocardial ceramide accumulation and disrupts cardiometabolic function”
24. 2016 Experimental Biology (poster)Presentation: “Gingival cell smoke exposure disrupts skeletal muscle metabolic function”
25. 2016 American Association of Dental Research (poster)Presentation: “Smoke exposure disrupts skeletal muscle metabolic function through oral gingiva”
26. 2015 Experimental Biology (poster)Presentation: “Ceramide-induced mitochondrial fission is necessary for sidestream cigarette smoke-induced cardiometabolic disruption”
27. 2015 Experimental Biology (poster)Presentation: “Macrophage-secreted ceramides are necessary for skeletal muscle mitochondrial disruption with LPS treatments”
28. 2015 Experimental Biology (poster)Presentation: “Macrophage-secreted ceramides are necessary for myocardial mitochondrial disruption with LPS treatments”
29. 2014 American Diabetes Association Scientific Sessions (oral)Presentation: “Mitochondrial fission is necessary for ceramide-induced metabolic disruption”
30. 2014 American Diabetes Association Scientific Sessions (poster)Presentation: “Ceramide is necessary for smoke-induced cardiomyocyte mitochondrial disruption”
31. 2014 American Diabetes Association Scientific Sessions (poster)Presentation: “Insulin increases ceramide biosynthesis in skeletal muscle”
32. 2014 American Diabetes Association Scientific Sessions (poster)Presentation: “Ceramide mediates cigarette smoke-induced metabolic disruption”
33. 2014 American Diabetes Association Scientific Sessions (poster)Presentation: “RAGE activation disrupts heart mitochondrial function”
34. 2014 Experimental Biology (poster)Presentation: “Mitochondrial fission is necessary for ceramide-induced metabolic disruption”
35. 2014 Experimental Biology (poster)Presentation: “Ceramide is necessary for smoke-induced cardiomyocyte mitochondrial disruption”
36. 2013 Experimental Biology (poster)Presentation: “Reactive oxygen species generation as a result of ceramide-induced mitochondrial fission”
37. 2013 Experimental Biology (poster)Presentation: “Ceramides as a mediator of cigarette smoke-induced metabolic disruption”
38. 2013 Experimental Biology (poster)Presentation: “Mitochondrial fission as a mediator of ceramide-induced metabolic disruption”
39. 2012 APS – Integrative Biology of Exercise (poster)Presentation: “AICAR selectively inhibits ceramide biosynthesis in skeletal muscle”
40. 2011 FASEB Summer Research Conferences – Glucose Transporters, Signaling, and Diabetes (poster)Presentation: “Dihydroceramide desaturase inhibition prevents ceramide accumulation and improves insulin sensitivity”
41. 2011 Keystone Symposium – Lipid Biology and Lipotoxicity (poster)Presentation: “Fenretinide improves insulin sensitivity by inhibiting dihydroceramide desaturase and preventing ceramide accumulation”
42. 2011 Singapore Annual Scientific Meeting in Translational Science (poster)Presentation: “Fenretinide improves insulin sensitivity by inhibiting dihydroceramide desaturase and preventing ceramide accumulation”
43. 2011 Keystone Symposium – Type 2 Diabetes, Insulin Resistance and Metabolic Dysfunction (poster)Presentation: “Resveratrol protects from lipid-induced insulin resistance, independent of Sirt1, via inhibition of ceramide”
44. 2010 Duke–NUS Research Symposium, Singapore (oral)Presentation: “Mechanism of inflammation-induced insulin resistance: Reliance of TLR4 action on ceramide synthesis reveals role for saturated fatty acids”
45. 2010 SingHealth–Duke–NUS Scientific Congress, Singapore (poster)Presentation: “Inflammation, lipids, and insulin resistance”
46. 2010 Meeting of the Asia-Pacific Diabetes/Obesity Study Group, Singapore (oral)Presentation: “Mechanism of inflammation-induced insulin resistance: Reliance of TLR4 action on ceramide synthesis reveals role for saturated fatty acids”
47. 2010 MGH–KI–Cell Days of Molecular Medicine, Stockholm, Sweden (oral)Presentation: “Mechanism of inflammation-induced insulin resistance: Reliance of TLR4 action on ceramide synthesis reveals role for saturated fatty acids”
48. 2009 American Diabetes Association Scientific Sessions, New Orleans, LA (oral)Presentation: “Lipid-induced insulin resistance is prevented in lean and obese myotubes with AICAR treatment”
49. 2008 APS Integrative Biology, Hilton Head, SC (poster)Presentation: “The effects of intrinsic aerobic capacity and diet on insulin signaling and IKKβ activity in rats”
50. 2008 American Diabetes Association Scientific Sessions, San Francisco, CA (poster)Presentation: “Insulin sensitivity improves after gastric bypass in the obese: A possible mechanism”
51. 2008 Experimental Biology, San Diego, CA (poster)Presentation: “A novel mechanism for metformin in improving insulin signaling in skeletal muscle”
52. 2005 ACSM National Meeting, Nashville, TN (oral)Presentation: “VO₂max and C-reactive protein in women”
Invited Community Presentations
1. 2025 BYU Wellness WeekPresentation: “The Worth of Souls”
2. 2023 BYU Wellness WeekPresentation: “Why we get sick: The metabolic origins of chronic disease”
3. 2022 Provo Rotary ClubPresentation: “What is insulin resistance and why does it matter?”
4. 2022 BYU Student Health CenterPresentation: “The role of insulin resistance in health”
5. 2020 Logan Swimmer’s AssociationPresentation: “Fuel Use and Performance”
6. 2020 BYU Men’s VolleyballPresentation: “Fuel Use and Performance”
7. 2020 Pacific Area, Church of Jesus Christ of Latter-day SaintsPresentation: “Why we get sick and what to do about it”
8. 2020 BYU Education WeekPresentation: “Why we get sick”
9. 2019 BYU Physical Facilities – Lunch and LearnPresentation: “Why we get sick and fat”
10. 2019 Utah Wellness SymposiumPresentation: “Why we get sick and fat”
11. 2019 YSA 3rd Stake, Church of Jesus Christ of Latter-day SaintsPresentation: “Insulin Resistance: Why we get fat and sick”
12. 2017 Orem Rotary ClubPresentation: “In defense of fat”
13. 2017 KetoConPresentation: “Insulin vs. Ketones: Battle for the Mitochondrion”
14. 2017 Canada’s Mormon Trail ChautauquaPresentation: “Why we get sick and fat: what to do about it”
15. 2017 Elderquest, Utah Valley UniversityPresentation: “Why we get sick and fat”
16. 2016 Southern Alberta ChautauquaPresentation: “The Plagues of Prosperity”
17. 2016 Brigham Young University PolicePresentation: “In Defense of Fat”
18. 2015 Brigham Young University – Diabetes ClubPresentation: “Diabetes, Insulin, and Ketones”
Publications
Published Manuscripts
- Withers PC, Jones A, Afran-Okese KB, Calder B, Morrill, HJ, Shafer TL, Nevers DS, Norby JH, Acosta R, Bikman BT, Suli A, Parrish RR. Pharmacological inhibition of all known major inward cationic currents does not block the induction of spreading depolarizations. Frontiers in Cellular Neuroscience, 2025, ID: 1668329.
- Palmer IL, Parker G, Chiu AT, Beus CG, Evans EP, Radford JH, Braithwaite CR, van Slooten RD, Cooper-Leavitt ET, Moore ZE, Clarke DM, Parrish RR, Arroyo JA, Reynolds PR, Bikman BT. 2025. RAGE knockout mitigates diet-induced obesity and metabolic disruption. Metabolites, 2025, 15, 524.
- Broberg E, English J, Clarke DM, Shin MJ, Bikman BT, Reynolds PR, Arroyo JA. Differential regulation of PKM2, AMPK, and mTOR in response to insulin and dietary management. Cells, 2025, 14, 416.
- Cooper-Leavitt ET, Shin MJ, Beus CG, Chiu AT, Parker G, Radford JH, Evans EP, Edwards IT, Arroyo JA, Reynolds PR, Bikman BT. The incretin effect of yerba maté (Ilex paraguariensis) is partially dependent on gut-mediated metabolism of ferulic acid. Nutrients, 2025, 17, 625.
- Beck L, Kirkham MN, Shin M, Bikman BT, Reynolds PR, Arroyo JA. Impact of secondhand smoke and e-cigarette exposure on placental apoptotic and growth-regulatory proteins in mouse pregnancy. Cells, 2025, 14, 453.
- Radford JH, Evans EP, Edwards IT, Arroyo JA, Bikman BT, Reynolds PR. Diesel particulate matter (DPM)-induced metabolic disruption in mice is mitigated by sodium copper chlorophyllin (SCC). Nutrients, 2025, 17, 717.
- Clarke DM, Kirkham MN, Beck LB, Campbell C, Alcorn H, Bikman BT, Arroyo JA, and Reynolds PR. 2024. Temporal RAGE over-expression disrupts lung development by modulating apoptotic signaling. Curr. Issues Mol. Biol., 2024, 46, 14453-14463.
- Remund NP, Larsen JG, Shin MJ, Warren CE, Palmer IL, Kim IJ, Cooper-Leavitt ET, Clarke DM, Beus, CG, Johnson RJ, Arroyo JA, Reynolds PR, Bikman BT. The role of ketones in mitigating the inflammatory and metabolic consequences of uric acid. Metabolites 2024, 14(12), 679.
- Clarke DM, Koutnik AP, Johnson RJ, DeBlasi JM, Bikman BT, Arroyo JA, Reynolds PR. Differential rates of glycation following exposure to unique monosaccharides. Int J Mol Sci 2024, 25, 6921.
- Curtis KL, Chang A, Johnston JD, Beard JD, Collingwood SC, LeCheminant JD, Peterson NE, South AJ, Farnsworth CB, Sanjel S, Bikman BT, Arroyo JA, Reynolds PR. Differential inflammatory cytokine elaboration in serum from brick kiln workers in Bhaktapr, Nepal. Diseases 2024, 12(6):129.
- Cayabyab KB, Shin MJ, Heimuli MS, Kim IJ, D’Agostino DP, Johnson RJ, Koutnik AP, Bellissimo N, Diamon DM, Norwitz NG, Arroyo JA, Reynolds PR, Bikman BT. The metabolic and endocrine effects of a 12-week allulose-rich diet. Nutrients 2024, 16(12), 1821.
- Kirkham M, Cooper C, Broberg E, Robertson P, Clarke D, Pickett B, Bikman BT, Reynolds PR, Arroyo JA. Different Lengths of Gestational Exposure to Secondhand Smoke or e-Cigarette Vapor Induces the Development of Placental Disease. Cells 2024, 13(12):1009.
- Clarke DM, Curtis KL, Harward K., Scott J, Stapley BM, Kirkham MN, Clark ET, Robertson P, Chambers E, Warren CE, Bikman BT, Arroyo JA, Reynolds PR. Embryonic Mice with Lung-Specific RAGE Upregulation have Enhanced Mitochondrial Respiration. J Respir 2024, 4, 140-151.
- Diamond D, Mason P, Bikman BT. Are mental health benefits of the ketogenic diet accompanied by an increased risk of heart disease. Frontiers in Nutrition 2024, doi.org/10.3389/fnut.2024.1394610
- Warren CE, Campbell KM, Kirkham MN, Saito ER, Remund NR, Cayabyab KB, Kim IJ, Heimuli MS, Reynolds PR, Arroyo JA, Bikman BT. The effect of diesel exhaust particles on adipose tissue mitochondrial function and inflammatory status. Int J Mol Sci 2024, 25(8), 4322.
- Curtis KL, Hirshi KM, Tsai K, Clark ET, Stapley BM, Bikman BT, Reynolds PR, Arroyo J. Postnatal Effects of Antenatal Secondhand Smoke (SHS) Exposure and the Receptor for Advanced Glycation End-products (RAGE). Reprod Med 2024, 5(1), 1-11.
- Deru LS, Gipson EZ, Hales KE, Bikman BT, Davidson LE, Horne BD, LeCheminant JD, Tucker LA, Bailey BW. The effects of a high-carbohydrate versus a high-fat shake on biomarkers of metabolism and glycemic control when used to interrupt a 38-hour fast: a randomized crossover study. Nutrients 2024, 16(1), 164.
- Carr ST, Saito ER, Walton CM, Saito JY, Hanegan CM, Warren CE, Trumbull AM, Bikman BT. Ceramides mediate insulin-induced impairments in cerebral mitochondrial bioenergetics in ApoE4 mice. Int J Mol Sci 2023, 24(23), 16635.
- Walton CM, Saito ER, Warren CE, Larsen JG, Remund NP, Reynolds PR, Hansen JM, Bikman BT. Yerba maté supplement exerts beneficial, tissue-specific effects on mitochondrial efficiency and redox status in healthy adult mice. Nutrients 2023, 15(20), 4454.
- Mendoza C, Hanegan C, Vargas L, Case T, Bikman BT, Mizrachi D. Insulin receptor-inspired soluble insulin binder. Euro J Cell Biol 2023. PMID: 36739671.
- Saito ER, Warren CE, Hanegan CM, Larsen JG, du Randt JD, Cannon M, Saito JY, Campbell RJ, Kemberling CM, Miller GS, Edwards JG, Bikman BT. A novel ketone-supplemented diet improves recognition memory and hippocampal mitochondrial efficiency in healthy adult mice. Metabolites 2022. PMID: 36355101
- Diamond D, Bikman BT, Mason P. Statin therapy is not warranted for a person with high LDL-cholesterol on a low-carbohydrate diet. Curr Opin Endocrinol Diabetes Obes 2022. PMID: 35938780.
- Bikman BT, Shimy KJ, Apovian CM, Yu S, Saito ER, Walton CM, Ebbeling CB, Ludwig DS. A high-carbohydrate diet lowers the rate of adipose tissue mitochondrial respiration. Euro J Clin Nutr 2022. PMID: 35177807.
- Deru LS, Bikman BT, Davidson LT, Tucker LA, Fellingham G, Bartholomew CL, Yuan HL, Bailey BW. The effects of exercise on β-hydroxybutyrate concentrations over a 36-h fast: a randomized crossover study. Med Sci Sports Exerc 2021. PMID: 33731648.
- Saito ER, Miller JB, Harari O, Cruchaga C, Mihindukulasuriya KA, Kauwe JSK, Bikman BT. Alzheimer’s disease alters oligodendrocyte glycolytic and ketolytic gene expression. Alzheimer’s & Dementia 2021. PMID: 33650792
- Walton CM, Jacobsen SM, Dallon BW, Saito ER, Bennett SLH, Davidson LE, Thomson DM, Hyldahl RD, Bikman BT. Ketones elicit distinct alterations in adipose mitochondrial bioenergetics. Int J Mol Sci 2020; 21(17):6255. (This manuscript was featured as the “highlight” article for the issue. This manuscript was rated the highest-downloaded article in the “biochemistry” section of the journal for 2020.)
- Hirschi KM, Tsai KYF, Davis T, Clark JC, Knowlton MN, Bikman BT, Reynolds PR, Arroyo JA. Growth arrest-specific protein-6/AXL signaling induces preeclampsia in rats. Biol Reprod 2020; 102(1):199-210.
- Chen T, Hill JT, Moore TM, Cheung ECK, Olsen ZE, Piorczynski TB, Marriott TD, Tessem JS, Walton CM, Bikman BT, Hansen JM, Thomson DM. Lack of skeletal muscle liver kinase B1 alters gene expression, mitochondrial content, inflammation and oxidative stress without affecting high-fat diet-induced obesity or insulin resistance. Biochemia et Biophysica 2020; 1866(8):165805.
- Ludwig DS, Ebbeling CB, Bikman BT, Johnson JD. Testing the Carbohydrate-Insulin Model in Mice: The Importance of Distinguishing Primary Hyperinsulinemia from Insulin Resistance and Metabolic Dysfunction. Mol Metab 2020; 35:100960.
- Gibbs JL, Dallon BW, Lewis JB, Walton CM, Arroyo JA, Reynolds PR, Bikman BT. Diesel exhaust particle exposure compromises macrophage mitochondrial physiology. Int J Mol Sci 2019; 20(22):5598.
- Mejia J, Hirschi K, Tsai KYF, Long M, Tullis B, Bitter EEK, Bikman BT, Reynolds PR, Arroyo JA. Differential placental ceramide levels during gestational diabetes mellitus (GDM). Reproductive Biology and Endocrinology 2019; 17(1):81.
- Walton CM, Perry K, Hart RH, Berry SL, Bikman BT. Improvements in glycemic and lipid profiles in type 2 diabetics with a 90-day ketogenic diet. Journal of Diabetes Research 2019; 8681959.
- Hirschi KM, Tsai KYF, Davis T, Clark JC, Knowlton MN, Bikman BT, Reynolds PR, Arroyo JA. Growth Arrest Specific Protein (Gas)-6/AXL Signaling Induces Preeclampsia (PE) in Rats. Biology of Reproduction 2019. PMID: 31347670.
- Fox JC, Evans AT, Blomfield MP, Livingstone SK, Tenney SR, Webster JB, Perry K, Hill JT, Bikman BT, Hansen MDH. Resistance mechanisms and cross-resistance for a pyridine-pyrimidine amide inhibitor of microtubule polymerization. Molecular Cancer Therapeutics 2019; 29(13): 1647-1653.
- Pape JA, Newey CR, Burrell HR, Workman A, Perry K, Bikman BT, Bridgewater LC, Grose JH. Per-Arnt-Sim Kinase (PASK) deficiency increases cellular respiration on a standard diet and decreases liver triglyceride accumulation on a western high-fat high-sugar diet. Nutrients 2018; 10(12):1990.
- DeMille D, Pape JA, Bikman BT, Ghassemian M, Grose JH. The regulation of Cbf1 by PAS Kinase is a pivotal control point for lipogenesis versus respiration in Sacchromyces cerevisiae. G3 (Bethesda) 2019; 29(13):1647-1653.
- Parker BA, Walton CM, Carr ST, Andrus JL, Cheung ECK, Duplisea MJ, Wilson EK, Draney C, Lathen DR, Kenner KB, Thomson DM, Tessem JS, Bikman BT. β-hydroxybutyrate elicits favorable mitochondrial changes in skeletal muscle. Int J Mol Sci 2018; 19(8): 2247.
- Dallon BW, Parker BA, Hodson AE, Tippetts TS, Harrison ME, Appiah MMA, Witt JE, Gibbs JL, Gray HM, Sant TM, Bikman BT. Insulin selectively reduces mitochondrial uncoupling in brown adipose tissue in mice. Biochem J 2018 475(3):561.
- Rowley TJ, Bitner BF, Ray JD, Lathen DR, Bikman BT, Hansen JM, Dorenkott MR, Goodrich KM, Ye L, O’Keefe SF, Neilson AP, Tessem JS. Monomeric cocoa catechins enhance β-cell function by increasing mitochondrial respiration. J Nutr Biochem 2017 49:30-41.
- Lindsley JE, Abali EE, Bikman BT, Cline SD, Fulton T, Lopez B, Rosenthal OD, Uhley VE, Weintraut RJ, Williams PD, Wisco JJ, Thompson K. What nutrition-related knowledge, skills, and attitude should medical students develop? Medical Science Educator 2017; 27(4) 579-583.
- Sampson MJ, Lathen DR, Dallon BW, Draney C, Ray JD, Kener KB, Parker BA, Gibbs JL, Gross JS, Tessem TS, Bikman BT. β-Hydroxybutyrate improves β-cell mitochondrial function and survival. J Ins Resist 2017; 2(1), a25.
- Banks CJ, Rodriguez NW, Gashler KR, Pandya R, Mortenson JB, Whited MD, Soderblom EJ, Thompson JW, Moseley MA, Reddi AR, Tessem JS, Torres MP, Bikman BT, Andersen JL. Acylation of Superoxide Dismutase 1 (SOD1) at K122 Governs SOD1-mediated Inhibition of Mitochondrial Respiration. Mol Cell Biol 2017; 37(20):e00354-17.
- Napa K, Baeder AC, Witt JE, Rayburn ST, Miller MG, Dallon BW, Gibbs JL, Wilcox SH, Winden DR, Smith JH, Reynolds PR, Bikman BT. LPS from P. gingivalis negatively alters gingival cell mitochondrial bioenergetics. Int J Dent 2017:2697210.
- Taylor OJ, Thatcher MO, Hubbard ST, Gibbs J, Trumbull AM, Gray HM, Winden DR, Pearson MJ, Tippetts TS, Holland WH, Reynolds PR, Bikman BT. High-mobility group box 1 disrupts metabolic function with cigarette smoke exposure in a ceramide-dependent manner. Int J Mol Sci. 2017; 18(5): 1099.
- Sanders NT, Dutson DJ, Durrant JW, Lewis JB, Wilcox SH, Winden DR, Arroyo JA, Bikman BT, Reynolds PR. Cigarette smoke extract (CSE) induces RAGE-mediated inflammation in the Ca9-22 gingival carcinoma epithelial cell line. Arch Oral Bio 2017; 80: 95-100.
- Lewis JB, Hirschi KM, Arroyo JA, Bikman BT, Kooyman DL, Reynolds PR. Plausible Roles for RAGE in Conditions Exacerbated by Direct and Indirect (Secondhand) Smoke Exposure. Int J Mol Sci. 2017 Mar 17;18(3)
- Mathis AD, Naylor BC, Carson RH, Evans E, Harwell J, Knecht J, Hexem E., Peelor III FF, Miller BF, Hamilton KL, Transtrum M, Bikman BT, Price JC. Mechanisms of in vivo ribosome maintenance respond to nutrient signals. Molecular and Cellular Proteomics 2017 16(2):243-254.
- Reynolds M, Hancock C, Ray J, Kener K, Draney C, Garland K, Hardman J, Bikman BT, Tessem J. β-cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion. Am J Physiol Endocrinol Metab 2016 311(1):E186-201.
- Braeder AC, Napa K, Richardson ST, Taylor OJ, Andersen SG, Wilcox SH, Winden DR, Reynolds PR, Bikman BT. Gingival cells exposed to cigarette smoke extract induce muscle cell metabolic disruption. International Journal of Dentistry 2016 ID 2763160.
- Hodson AE, Tippetts TS, Bikman BT. Insulin treatment increases myocardial ceramide accumulation and disrupts cardiometabolic function. Cardiovascular Diabetology 2015; 14(1):153.
- Hansen ME, Thatcher MO, Simmons KJ, Tippetts TS, Saito RR, Trumbull AM, Taylor OJ, Hubbard ST, Bikman BT. Lipopolysaccharide Disrupts Mitochondrial Physiology in Skeletal Muscle via Disparate Effects on Sphingolipid Metabolism. Shock 2015; 44(6):585-92.
- Kwon OS, Tanner RE, Barrows KM, Runtsch M, Symons JD, Jalil T, Bikman BT, McClain DA, O’Connell RM, Drummond MJ. MyD88 regulates physical inactivity-induced skeletal muscle inflammation, ceramide biosynthesis signaling and glucose tolerance. Am J Physiol Endocrinol Metab 2015; 309(1):E11-21.
- Nelson MB, Swensen AC, Winden DR, Bodine JS, Bikman BT, Reynolds PR. Receptor for advanced glycation end-products (RAGE) signaling reduces cardiomyocyte mitochondrial function in a ceramide-dependent manner. Am J Physiol Heart 2015; 309(1):H63-9.
- Gibby JT, Njeru DK, Cvetko ST, Merrill RM, Bikman BT, Gibby WA. Volumetric analysis of central body fat accurately predicts incidence of diabetes and hypertension in adults. BMC Obesity 2015; 2:10.
- Tippetts TS, Winden DR, Swensen AC, Nelson MB, Thatcher MO, Saito RR, Condie TB, Simmons KJ, Judd AM, Reynolds PR, Bikman BT. Cigarette smoke increases cardiomyocyte ceramide accumulation and inhibits mitochondrial respiration. BMC Cardiovasc Disord 2014 Nov 22;14:165.
- Thatcher MO, Tippetts TS, Nelson MB, Swensen AC, Winden DR, Hansen ME, Johnson IE, Porter JP, Prince JT, Reynolds PR, Bikman BT. Ceramides mediate cigarette smoke-induced metabolic disruption in mice. Am J Physiol Endocrinol Metab. 2014 307(10):E919-27. (This manuscript was ranked #15 on the APS annual ranking of “most shared” manuscripts among all physiology publications through online search portals, social media, news outlets, etc.)
- DeMille D, Bikman BT, Mathis AD, Prince JT, Mackay JT, Sowa SW, Hall TD, Grose JH. A Comprehensive Protein-protein Interactome for Yeast PAS Kinase 1 Reveals Direct Inhibition of Respiration through the Phosphorylation of Cbf1. Mol Biol Cell 2014 May 21. pii: mbc.E13-10-0631.
- Hansen ME, Tippetts TS, Moulton ER, Holub ZE, Swensen AC, Prince JT, Bikman BT. Insulin increases ceramide biosynthesis and accumulation in skeletal muscle. J Diabetes Res 2014; Article ID 765784.
- Smith ME, Tippetts TS, Brassfield ES, Tucker BJ, Ockey A, Swensen AC, Anthonymuthu TS, Washburn TD, Kane DA, Prince JT, Bikman BT. Mitochondrial fission mediates ceramide-induced metabolic disruption in skeletal muscle. Biochem J 2013; 456(4):427-439. (Highlighted as one of three “high-impact” manuscripts in the issue.)
- Erickson KA, Smith ME, Anthonymuthu TS, Evanson MJ, Brassfield ES, Hodson AE, Bressler MA, Tucker BJ, Thatcher MO, Prince JT, Hancock CR, Bikman BT. AICAR inhibits ceramide biosynthesis in skeletal muscle. Diabetol Metab Syndr 2012; 4(9):45.
- Siddique MM, Bikman BT, Wang L, Ying L, Reinhardt E, Shui G, Wenk MR, Summers SA. Ablation of dihydroceramide desaturase confers resistance to Etoposide-induced apoptosis in vitro. PLoS One. 2012; 7(9):e44042.
- Bikman BT, Guan YG, Shui G, Siddique MM, Kim JY, Wenk MR, Summers SA. Fenretinide prevents lipid-induced insulin resistance by blocking ceramide synthesis. J Biol Chem 2012; 287:17426-37.
- Bikman BT. A Role for Sphingolipids in the Pathophysiology of Obesity-induced Inflammation. Cell Mol Life Sci 2012; 69:2135-46.
- Bikman BT and Summers SA. Ceramides as modulators of cellular and whole-body metabolism. J Clin Invest 2011 121(11): 4222-4230.
- Bikman BT and Summers SA. Sphingolipids and Hepatic Steatosis. Adv Exp Med Biol 2011 721: 87-97.
- Holland WL*, Bikman BT*, Wang LP, Liu Y, Sargent KM, Knotts TA, Pagliasotti MJ, Shui G, Wenk MR, Scherer PE, Summers SA. Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice. J Clin Invest 2011 121(5): 1858–1870. * co-first author
- Holland WL, Miller RA, Wang ZV, Sun K, Barth B, Bui HH, Davis KE, Bikman BT, Halberg N, Rutkowski JM, Wade MR, Tenorio VM, Kuo M-S, Brozinick JT, Zhang BB, Birnbaum MJ, Summers SA, Scherer PE. Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin. Nat Med 2011 17(1):55-63.
- Kane DA, Anderson EJ, Woodlief TL, Price III JW, Bikman BT, Cortright, RN and Neufer PD, Metformin Selectively Attenuates Mitochondrial H2O2 Emission without Affecting Respiratory Capacity in Skeletal Muscle of Obese Rats. Free Radic Biol Med 2010; 49(6): 1082-1087.
- Bikman BT, Zheng D, Reed MA, Hickner RC, Houmard JA, Dohm GL. Lipid-induced insulin resistance is prevented in lean and obese myotubes with AICAR treatment. Am J Physiol Regulatory Integrative Comp Physiol 2010; 298: R1692-R1699.
- Bikman BT, Zheng D, Cortright RN, Neufer PD, Kane DA, Anderson EJ, Woodlief TL, Price JW, Dohm GL. Metformin Improves Skeletal Muscle Insulin Signaling in Obese Rats in a Fiber-type Dependent Manner. J Obes 2010 (Epub 2010 Jan 14).
- Bikman BT, Woodlief TL, Noland RC, Lust RM, Dohm GL, Cortright RN. High-fat diet induces IKKbeta and reduces insulin sensitivity in rats with low running capacity. Int J Spor Med 2009; 30: 631-635.
- Bikman BT, Zheng D, Pories WJ, Chapman WH, Pender J, Bowden R, Reed MA, Cortright RN, Tapscott EB, Houmard JA, Tanner CJ, Lee J, Dohm GL. Mechanism(s) for Improved Insulin Sensitivity After Gastric Bypass Surgery. J Clin Endo Metab 2008; 93: 4656-4663.
- Stob NR, Seals DR, Jensen J, van Baak MA, Steig AJ, Lindstrom RC, Bikman BT, Bell C. Increased Thermogenic Responsiveness to Intravenous Beta-Adrenergic Stimulation in Habitual Exercisers is Not Related to Skeletal Muscle Beta2-Adrengergic Receptor Density. Experimental Physiology 2007; 92: 823-830.
Book Chapters
- Bikman BT and Summers SA. Sphingolipids and Hepatic Steatosis, in: Sphingolipids and metabolic diseases, 2010, Landes Biosciences.
Magazine Articles
- Bressler MA and Bikman BT. Inflammation and the Metabolic Syndrome. Asia Pacific Biotech News. December 2011.
Books
- “Why we get sick: The hidden epidemic at the root of most chronic disease—and how to fight it.” BenBella Publishing 2020.
- “How not to get sick.” BenBella Publishing, 2024